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the t1/2 of PT2385 is 3
and dendritic cells in relevant tissues
Smiles: [Na]
InChiKey: JXXCENBLGFBQJM-FYZOBXCZSA-N
5H-pyrazolo[3
LYN-1604 ioxaundecanedioic Acid the t1/2 of PT2385 isLYN 1604 is a potential ULK1 agonist with IC50 of 1. 66 M against MDA MB 231 cells and it binds to wild type ULK1 with a binding affinity in the nanomole range (Kd=291. 4 nM). The ULK1 (Y89A) mutant protein caused a sharp decrease in binding affinity with lower response and Kd than wild type ULK1, ULK1 (K50A) and ULK1 (L53A) mutants. Product information CAS Number: 2088939 99 3 Molecular Weight: 584. 62 Formula: C33H43Cl2N3O2 Chemical Name: 2 [bis(2
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